Process Scale-Up Calculator
Scale reactor agitation from lab to production using constant tip speed, constant P/V, or constant Reynolds number criteria.
Inputs
L
L
RPM
W
(1=tip speed, 2=P/V, 3=Re)
Results
Volume Scale Ratio
1,000×
Production Agitator Speed
30 RPM
Production Power500 W
Impeller Diameter0.6 m
Estimated Mixing Time2 s
How to Use This Calculator
- Enter the Lab Reactor Volume in liters and the target Production Reactor Volume in liters — the ratio defines the scale-up factor.
- Enter the Lab Agitator Speed in RPM and Lab Agitator Power in watts from bench-scale testing.
- Select the Scale-Up Criterion: 1 = constant tip speed (good for shear-sensitive processes), 2 = constant power per volume (good for mass transfer), 3 = constant Reynolds number (preserves mixing pattern).
- Review the Production Agitator Speed in RPM and Production Power in watts to specify the production agitator motor.
- Note the Impeller Diameter in meters to specify the production vessel and agitator geometry.
- Use the Estimated Mixing Time in seconds to assess blend time and ensure homogeneity at production scale.
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