Parenteral Nutrition Calculator
Formulate a TPN prescription by calculating dextrose, amino acid, and lipid volumes and calories. Includes glucose infusion rate (GIR) and NPC:N ratio checks.
Medical Disclaimer
This calculator is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about your health. Never disregard professional medical advice or delay seeking it because of results from this tool.
Step 1 of 2
How to Use This Calculator
- Enter the patient's weight in kg and daily caloric goal in kcal.
- Set the protein goal in g/kg/day as prescribed.
- Enter the percentage of non-protein calories from lipid emulsion.
- Review the dextrose, amino acid, and lipid volumes to ensure they meet the prescription.
- Verify osmolarity before administration; confirm with the pharmacy and care team.
How the result changes with Caloric goal (kcal/day)
| Caloric goal (kcal/day) | Total calories (kcal/day) |
|---|---|
| 950 | 950 |
| 2,075 | 2,075 |
| 3,425 | 3,425 |
| 4,550 | 4,550 |
What each input means
- Weight (kg)
- Patient body weight in kilograms.
- Caloric goal (kcal/day)
- Target daily calorie delivery.
- Protein goal (g/kg/day)
- 0.8 = maintenance, 1.2 = moderate stress, 1.5-2.0 = critical illness or burns.
- Lipid % of non-protein calories
- Typically 20-30% of non-protein calories from lipid emulsion.
- Dextrose concentration (%)
- Central line allows up to D70; peripheral max ~D10.
- Volume target (mL/day)
- Target total daily fluid volume for TPN bag.
What each result means
- Total calories (kcal/day)
- Total caloric delivery from the TPN formulation.
- Amino acids (g/day)
- Total protein from amino acid solution.
- Dextrose (g/day)
- Grams of dextrose providing non-protein carbohydrate calories.
- Lipid (g/day)
- Grams of IV lipid emulsion.
- Amino acid volume (mL)
- Volume of 10% amino acid solution.
- Dextrose volume (mL)
- Volume of dextrose solution at specified concentration.
- Lipid emulsion volume (mL)
- Volume of 20% lipid emulsion.
- Total macro volume (mL)
- Combined volume of all macronutrient solutions.
- Glucose infusion rate (mg/kg/min)
- Target < 4-5 mg/kg/min for adults to avoid hyperglycemia.
- NPC:N ratio
- Non-protein calories to nitrogen ratio. Target 100-150:1 (80-100:1 in stress).
How this is calculated
Worked example, using the default values
- Identify Input Parameters4 parametersWeight (kg) = 70, Caloric goal (kcal/day) = 2000, Protein goal (g/kg/day) = 1.2, Lipid % of non-protein calories = 25 = 6 input(s) provided
- Calculate Total calories2000 = 2000
- Calculate Amino acidsAmino acids = proteinGoalPerKg * weightKg84 = 84
- Calculate DextroseDextrose367 = 367
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