Skip to main content
Calcimator

Anticoagulation Calculator

Warfarin dose adjustment calculator based on current INR, target range, and weekly dose with recheck interval recommendations.

About this calculator

This calculator suggests a warfarin dose adjustment, recheck interval, and bleeding-risk category from a current INR compared against a target range (rather than a single target value), using a simplified empiric percentage-based nomogram similar in style to common hospital dosing protocols. Below the target range, the suggested increase grows with how far below and how low the absolute INR is (5% for a small gap, 10% for a larger gap, 15% once INR is both below the target's low bound and under 1.5). Note that the 15% step only ever applies to an INR that is ALSO below the target's low bound: if a clinician sets a lower target-low bound, such as 1.0, an INR between that bound and 1.5 is not automatically boosted to the 15% step -- it may instead read as in-range with no adjustment suggested at all. Above the target range, the suggested decrease similarly grows with severity, culminating in a full hold (-100%, reducing the suggested dose to zero) for any INR over 5.0 -- this calculator does not distinguish a brief hold from stopping therapy entirely, and does not add vitamin K guidance, which real supratherapeutic-INR protocols often include at higher INR levels or with bleeding.

Within the target range, no adjustment is suggested and the recheck interval extends to monthly, reflecting a stable result. The bleeding risk category is a simplified banding of the absolute INR level alone (low up to 3.0, moderate 3-4, high 4-5, critical above 5), independent of the patient's target range, indication, or other bleeding risk factors such as age, prior bleeding, or interacting medications -- none of which this calculator collects. Current weekly dose only scales the suggested new dose; it never changes which percentage band, recheck interval, or bleeding-risk category applies. This is a decision-support estimate, not a substitute for individualized anticoagulation management.

Inputs

mg

Results

Dose Adjustment

0%

New Weekly Dose

35 mg

New Average Daily Dose5 mg
Recheck INR In28 days
Current Status1
Bleeding Risk Level0
How to Use This Calculator
  1. Enter the patient's most recent INR result.
  2. Set the target INR range (low and high bounds) for the indication.
  3. Enter the current weekly warfarin dose in mg.
  4. Review Dose Adjustment (%), New Weekly Dose (mg), and Recheck INR In (days).
  5. For clinical use — always apply clinical judgment; this tool supports but does not replace provider decisions.

What each input means

Current INR
Most recent INR lab result.
Target INR (low)
Lower bound of target INR range. Typically 2.0 for AFib/DVT, 2.5 for mechanical valves.
Target INR (high)
Upper bound of target INR range. Typically 3.0 for AFib/DVT, 3.5 for mechanical valves.
Current weekly dose
Total warfarin dose per week (sum of all daily doses).

What each result means

Dose Adjustment
Suggested % change in weekly dose. -100% means hold warfarin.
New Weekly Dose
Suggested new total weekly warfarin dose.
New Average Daily Dose
New weekly dose divided by 7.
Recheck INR In
Recommended days until next INR check.
Current Status
0 = Sub-therapeutic, 1 = Therapeutic, 2 = Supra-therapeutic.
Bleeding Risk Level
0 = Low (INR ≤3), 1 = Moderate (3-4), 2 = High (4-5), 3 = Critical (>5).

How this is calculated

Worked example, using the default values

  1. Identify Input Parameters
    4 parameters
    Current INR = 2.5, Target INR (low) = 2, Target INR (high) = 3, Current weekly dose = 35 = 4 input(s) provided
  2. Calculate Dose Adjustment
    Dose Adjustment
    0 = 0
  3. Calculate New Weekly Dose
    35 = 35
  4. Calculate New Average Daily Dose
    New Average Daily Dose = newWeeklyDose / 7
    5 = 5
  5. Calculate Recheck INR In
    Recheck INR In
    28 = 28

Engine last updated . Checked against 2 independently-derived tests — how we verify calculators. Built by Paul Gunder, a software engineer, not a licensed financial, medical, or legal professional.

Frequently Asked Questions

How is this different from a warfarin calculator that uses a single target INR?

This calculator compares the current INR against a full target RANGE (a low and high bound) rather than one target number, so any INR that falls anywhere inside that range is treated as therapeutic with no adjustment suggested -- not just a single exact value. Target ranges typically run 2.0-3.0 for atrial fibrillation or DVT/PE and a higher 2.5-3.5 for mechanical heart valves.

What happens when INR is above 5.0?

The calculator suggests a full hold -- a -100% adjustment, meaning the new weekly dose drops to zero -- and shortens the recheck interval to the next day. It does not distinguish a brief one-to-two-dose hold from stopping therapy entirely, and it does not add vitamin K dosing guidance, which many real protocols include at this INR level, particularly if there's any bleeding.

Does the current weekly dose affect the bleeding risk category or recheck interval?

No. Bleeding Risk Level and Recheck INR In are both determined purely by where the current INR falls relative to the target range and the absolute INR value -- the current weekly dose only scales the suggested New Weekly Dose once the percentage adjustment has already been determined, it never changes which risk category or recheck timeline applies.

Why does the recheck interval get shorter as INR moves further from target?

A larger deviation from target -- either well below or well above the range -- carries more clinical urgency, since a very low INR leaves a patient under-anticoagulated and a very high INR raises bleeding risk. The suggested recheck interval tightens accordingly, from a monthly check when stable in range down to the very next day for an INR over 5.0.

The questions that sit next to this one — chosen by subject, including calculators filed under a different category.

More in Medical & Clinical.