Valve Area Calculator
Calculate aortic or mitral valve area using the Gorlin equation from cardiac catheterization data.
About this calculator
The Gorlin equation, published by Richard Gorlin and Sidney Gorlin in 1951, was the original method for converting cardiac catheterization pressure and flow measurements into an actual valve orifice area, and a version of it is still used today alongside modern echocardiographic methods. The core idea is that flow through a fixed orifice relates to the pressure gradient driving that flow -- a smaller, more stenotic orifice needs a larger pressure gradient to push the same amount of blood through it, so measuring flow and gradient together lets you back-calculate the effective orifice area. This calculator computes flow across the valve from cardiac output, heart rate, and the relevant time period (systolic ejection period for the aortic valve, diastolic filling period for the mitral valve, since that is when each valve is actually open and conducting flow), then divides by an empirical constant times the square root of the mean pressure gradient. The constant differs by valve because the underlying discharge coefficient -- how efficiently flow actually passes through the anatomic orifice compared to an idealized opening -- differs between the two valves: 44.3 for the aortic valve, and 37.7 for the mitral valve (the 1972 Cohen-Gorlin revision, using a 0.85 discharge coefficient for the mitral valve rather than the original 0.7). For aortic stenosis, a calculated valve area above 2.0 cm² is considered normal, 1.5-2.0 cm² mild, 1.0-1.5 cm² moderate, and below 1.0 cm² severe.
Mitral stenosis grading follows the ACC/AHA 2020 valvular heart disease guideline: valve area above 2.5 cm² is not considered hemodynamically significant, 2.0-2.5 cm² mild, 1.5-2.0 cm² moderate, and 1.5 cm² or below severe (with 1.0 cm² or below further classified as very severe). Note that these bands describe the degree of narrowing relative to when stenosis becomes hemodynamically meaningful, not the mitral valve's true undiseased anatomic size, which is considerably larger (roughly 4-6 cm²). This calculator also reports a velocity derived from the simplified Bernoulli equation (v = √(ΔP/4)) using the same mean pressure gradient entered above. Because it is derived from the *mean* gradient rather than a directly measured Doppler *peak* velocity, it reads meaningfully lower than a true peak velocity at the same severity and should not be compared directly against peak-velocity severity cutoffs (such as the ≥4.0 m/s threshold used for severe aortic stenosis) -- ΔP = 4v² is the standard relationship used at the bedside to convert a Doppler-measured velocity into a pressure gradient, or vice versa, but a true peak-velocity estimate requires the peak instantaneous gradient, not the mean.
Medical Disclaimer
This calculator is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about your health. Never disregard professional medical advice or delay seeking it because of results from this tool.
Inputs
Results
Valve Area
0.79 cm²
Stenosis Grade
3
Figures current as of 2020. Sources: Gorlin R, Gorlin SG. Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. Am Heart J. 1951;41(1):1-29., Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease. Circulation. 2021;143(5):e72-e227.
How to Use This Calculator
- Enter cardiac output (L/min), heart rate (bpm), and systolic ejection period or diastolic filling period (ms).
- Set mean transvalvular pressure gradient (mmHg) and select valve type (aortic or mitral).
- Review Valve Area (cm²), Stenosis Grade, Transvalvular Flow (mL/s), and Mean-Gradient-Derived Velocity (m/s).
- Aortic valve area < 1.0 cm² = severe stenosis; mitral valve area <= 1.5 cm² = severe stenosis (<= 1.0 cm² very severe).
How the result changes with Cardiac output
| Cardiac output | Valve Area | Stenosis Grade |
|---|---|---|
| 2.5 | 0.4 cm² | 3 |
| 3.75 | 0.59 cm² | 3 |
| 7.5 | 1.19 cm² | 2 |
| 13 | 2.06 cm² | 0 |
What each input means
- Cardiac output
- Cardiac output measured by Fick or thermodilution.
- Heart rate
- Heart rate during catheterization.
- Systolic ejection period (or DFP)
- Systolic ejection period for aortic valve; diastolic filling period for mitral valve.
- Mean pressure gradient
- Mean transvalvular pressure gradient from catheterization or echo.
- Valve
- Selects which valve is being assessed. Adjusts the Gorlin constant and the stenosis grading bands.
What each result means
- Valve Area
- Calculated valve orifice area. Aortic: no significant stenosis >2.0 cm². Mitral: no significant stenosis >2.5 cm² (true anatomic normal is 4-6 cm²).
- Stenosis Grade
- 0 = Normal, 1 = Mild, 2 = Moderate, 3 = Severe.
- Transvalvular Flow
- Volume flow rate across the valve per ejection/filling period.
- Mean-Gradient-Derived Velocity
- Velocity derived from the simplified Bernoulli equation applied to the MEAN pressure gradient entered above: v = √(ΔP/4). This is not the true Doppler peak velocity, which is derived from the peak gradient and reads higher -- do not compare this figure to peak-velocity severity cutoffs.
How this is calculated
Worked example, using the default values
- Identify Input Parameters4 parametersCardiac output = 5, Heart rate = 75, Systolic ejection period (or DFP) = 300, Mean pressure gradient = 40 = 5 input(s) provided
- Calculate Valve AreaValve Area = flowPerPeriod / (gorlinConstant * sqrt(meanGradient))0.79 = 0.79
- Calculate Stenosis Grade3 = 3
- Calculate Transvalvular FlowTransvalvular Flow = (cardiacOutput * 1000) / (heartRate * sepSec)222 = 222
- Calculate Mean-Gradient VelocityMean-Gradient Velocity = sqrt(meanGradient / 4)3.16 = 3.16
Figures and sources
- Gorlin equation for valve area from catheterization pressure and flow (1951) — Gorlin R, Gorlin SG. Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. Am Heart J. 1951;41(1):1-29.
- 2020 ACC/AHA valvular heart disease guideline (mitral stenosis severity grading) (2020) — Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease. Circulation. 2021;143(5):e72-e227.
Engine last updated . Checked against 1 independently-derived test — how we verify calculators. Built by Paul Gunder, a software engineer, not a licensed financial, medical, or legal professional.
Frequently Asked Questions
Why does the Gorlin constant differ between the aortic and mitral valve?
The Gorlin constant folds together a fixed physical term (related to blood acceleration under gravity) and an empirical discharge coefficient that reflects how efficiently flow actually passes through each valve's real anatomic orifice compared to an idealized opening of the same size. The mitral valve's discharge coefficient (0.85 in the widely used 1972 Cohen-Gorlin revision) differs from the aortic valve's, which is why the constants work out to roughly 44.3 for the aortic valve and 37.7 for the mitral valve rather than a single shared value.
Why does the calculator use systolic ejection period for the aortic valve but diastolic filling period for the mitral valve?
Flow only occurs across a valve while it is actually open and conducting blood -- the aortic valve opens during systole as the left ventricle ejects blood, while the mitral valve opens during diastole as the left ventricle fills. Using the wrong period (or the whole cardiac cycle) would understate the true instantaneous flow rate through the valve, since it would spread the same total volume across a longer time window than the valve is actually open for.
How is the mean-gradient-derived velocity different from a true Doppler peak velocity?
The simplified Bernoulli equation (v = √(ΔP/4), equivalently ΔP = 4v²) converts a pressure gradient into an estimated blood velocity, or vice versa. This calculator only collects a *mean* transvalvular gradient, so the velocity it reports is derived from that mean gradient -- it is not the true Doppler peak velocity, which is derived from the peak instantaneous gradient and runs meaningfully higher (for example, a true peak velocity is roughly 4.0-4.4 m/s at a 40 mmHg mean gradient, versus about 3.16 m/s for the mean-gradient-derived figure this calculator shows). Do not compare this calculator's velocity output directly against peak-velocity severity cutoffs such as the ≥4.0 m/s threshold for severe aortic stenosis; use the Valve Area and Stenosis Grade outputs for severity instead.
Why does mitral stenosis use a much higher 'normal' valve area than aortic stenosis?
The mitral valve's native, undiseased orifice is considerably larger than the aortic valve's -- true anatomic mitral valve area is roughly 4-6 cm² compared to roughly 3-4 cm² for a normal aortic valve. This calculator's severity bands describe the degree of acquired narrowing relative to each valve's own baseline rather than a shared cutoff, so the "no significant stenosis" band for the mitral valve (above 2.5 cm²) sits well below the mitral valve's true undiseased size -- a mitral valve area that would already represent significant aortic stenosis (say, 2 cm²) is only mild mitral stenosis, because it is still much closer to the mitral valve's own normal range.
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