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ECOG Performance Status Calculator

Score ECOG performance status, convert to Karnofsky (KPS), assess treatment eligibility, and calculate the Palliative Prognostic Index (PPI).

About this calculator

ECOG performance status is a 0-to-5 scale oncologists use to describe how much a patient's daily activity is limited by their disease, running from fully active (0) through progressively more restricted (1-4) to deceased (5). It is one of the most widely used eligibility gates in oncology: most Phase I clinical trials require ECOG 0-1, standard-dose chemotherapy protocols are typically restricted to ECOG 0-2, and an ECOG of 3 or higher generally shifts the conversation toward palliative-focused care rather than aggressive disease-directed treatment. This calculator converts the entered ECOG grade to its approximate Karnofsky Performance Scale (KPS) equivalent for comparison with older literature that still reports KPS, and separately computes the Palliative Prognostic Index (PPI, Morita et al.), which combines performance status with four symptom factors -- oral intake, peripheral edema, dyspnea at rest, and delirium -- into a score used to estimate short-term survival in advanced illness.

The PPI was originally built from the Palliative Performance Scale (PPS), a separate 0-100% functional-status scale used in hospice and palliative care; this calculator substitutes ECOG for PPS in that performance-status component (ECOG 4-5 scoring the same 4.0 points that PPS <=10% earns) as a practical approximation, since ECOG is the scale collected elsewhere on this page -- treat the resulting PPI as an approximation of the published PPS-based score rather than an exact reproduction. A PPI above 6 is associated with survival under roughly three weeks, above 4 up to 6 with under roughly six weeks, and 4 or below with survival typically beyond six weeks. Both scales are clinical judgment aids, not precise survival predictions, and neither substitutes for a full oncologic and palliative care assessment.

Inputs

Results

ECOG Performance Status

1

Karnofsky (KPS) estimate

80

Palliative Prognostic Index0
Estimated prognosis (weeks)12
Phase I trial eligible (0/1)1
Standard chemo eligible (0/1)1
Palliative care only (0/1)0

Figures current as of 1982. Source: Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649-655.

How to Use This Calculator
  1. Select the ECOG score that best describes the patient's current functional capacity, from 0 (fully active) to 5 (deceased).
  2. Select Oral intake, Edema present, Dyspnea at rest, and Delirium present to compute the Palliative Prognostic Index (PPI).
  3. Review the ECOG score and its Karnofsky (KPS) equivalent for comparison with older literature.
  4. Check Phase I trial, standard chemotherapy, and palliative-only eligibility flags for treatment planning.
  5. Review the PPI score and its associated rough survival-time band — higher PPI corresponds to shorter estimated survival.

What each input means

ECOG score
Eastern Cooperative Oncology Group performance status grade.
Oral intake
Current oral intake level, used for the Palliative Prognostic Index.
Edema present
Presence of peripheral edema.
Dyspnea at rest
Breathlessness at rest.
Delirium present
Presence of delirium or altered consciousness.

What each result means

ECOG Performance Status
0–5 scale (lower is better functional status).
Karnofsky (KPS) estimate
Approximate Karnofsky score (0–100, higher is better).
Palliative Prognostic Index
PPI score (Morita et al., approximated here using ECOG in place of PPS): >6 = <3 wk survival, >4–6 = <6 wk, ≤4 = >6 wk.
Estimated prognosis (weeks)
Rough survival estimate based on PPI score.
Phase I trial eligible (0/1)
Most phase I trials require ECOG 0–1.
Standard chemo eligible (0/1)
Standard chemotherapy typically requires ECOG 0–2.
Palliative care only (0/1)
ECOG 3–4 generally indicates palliative-only approach.

How this is calculated

Worked example, using the default values

  1. Identify Input Parameters
    4 parameters
    ECOG score (0–5) = 1, Oral intake (0=normal, 1=reduced, 2=mouthfuls) = 0, Edema present (0=no, 1=yes) = 0, Dyspnea at rest (0=no, 1=yes) = 0 = 5 input(s) provided
  2. Calculate ECOG Performance Status
    ECOG Performance Status = 1
    1 = 1
  3. Calculate Karnofsky (KPS) estimate
    Karnofsky (KPS) estimate
    80 = 80
  4. Calculate Palliative Prognostic Index
    Palliative Prognostic Index
    0 = 0
  5. Calculate Estimated prognosis
    12 = 12

Figures and sources

Engine last updated . Checked against 3 independently-derived tests — how we verify calculators. Built by Paul Gunder, a software engineer, not a licensed financial, medical, or legal professional.

Frequently Asked Questions

What ECOG score is typically required for a Phase I clinical trial?

Most Phase I trials require an ECOG performance status of 0 or 1, reflecting the need for patients to tolerate a novel, potentially more toxic therapy without severe pre-existing functional limitation. This calculator flags Phase I eligibility only at ECOG 0 or 1, separately from the wider ECOG 0-2 threshold it uses for standard-dose chemotherapy eligibility.

How is ECOG performance status different from the Palliative Prognostic Index?

ECOG performance status describes functional capacity alone, on a single 0-to-5 scale. The Palliative Prognostic Index is a separate, broader score that adds four symptom factors -- oral intake, edema, dyspnea at rest, and delirium -- on top of performance status, producing a composite number this calculator maps to a rough survival-time band rather than a functional-capacity grade.

Which single factor contributes most to a high PPI score?

Delirium and a severely limited performance status (ECOG 4, bedbound) each contribute the largest single share to this calculator's PPI score, roughly tied with each other and larger than any one symptom factor alone. ECOG 5 (deceased) scores the same as ECOG 4 in this formula, though a PPI calculation is only clinically meaningful for a living patient. Dyspnea at rest contributes the next largest share, with edema and reduced oral intake adding smaller amounts.

Does a KPS score of 60 mean the same thing as an ECOG score of 2?

Approximately, yes -- they sit on the same general point of the traditional ECOG-to-KPS conversion table this calculator uses, but the two scales aren't identical in granularity: ECOG has six whole-number grades (0-5) while KPS uses ten-point increments (0-100), so a given ECOG grade maps to one representative KPS value rather than a precise one-to-one conversion.

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