Renal Dose Adjustment Calculator
Estimate dose modifications based on glomerular filtration rate (GFR) for renally-cleared medications.
Medical Disclaimer
This calculator is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about your health. Never disregard professional medical advice or delay seeking it because of results from this tool.
Inputs
Results
Adjusted Dose
500 mg
Adjusted Interval
8 hours
How to Use This Calculator
- Enter Normal Dose, Normal Dosing Interval, and GFR (eGFR).
- Review Adjusted Dose (mg) and Adjusted Interval (hours).
- Use Dose Reduction (%) and Renal Stage (1=Normal, 5=ESRD) to inform your decision.
How the result changes with Normal Dose
| Normal Dose | Adjusted Dose | Adjusted Interval |
|---|---|---|
| 501 | 501 mg | 8 hours |
| 1,751 | 1,751 mg | 8 hours |
| 3,250 | 3,250 mg | 8 hours |
| 4,500 | 4,500 mg | 8 hours |
What each input means
- Normal Dose
- Standard dose of the medication for normal renal function (in mg).
- Normal Dosing Interval
- Standard dosing frequency in hours (e.g., every 8 hours).
- GFR (eGFR)
- Estimated glomerular filtration rate in mL/min/1.73m².
How this is calculated
Worked example, using the default values
- Identify Input ParametersNormal Dose = 500, Normal Dosing Interval = 8, GFR (eGFR) = 90 = 3 input(s) provided
- Calculate Adjusted DoseAdjusted Dose500 = 500
- Calculate Adjusted IntervalAdjusted Interval8 = 8
- Calculate Dose ReductionDose Reduction0 = 0%
- Calculate Renal StageRenal Stage1 = 1
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