Insulin Sensitivity Calculator

HOMA-IR from fasting glucose and insulin.

Medical Disclaimer

This calculator is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about your health. Never disregard professional medical advice or delay seeking it because of results from this tool.

Inputs

Fasting Insulin (µU/mL)

Fasting Glucose (mg/dL)

HbA1c (%)

Tab to move between fields

Results

HOMA-IR

1.78

HOMA-%B (β-cell function)106.7

QUICKI0.35

Est. Average Glucose (mg/dL)114

Resistance Level (0–3)1

How to Use This Calculator

Enter Fasting Insulin (uU/mL) and Fasting Glucose (mg/dL) from a morning fasting lab draw.
Input HbA1c (%) from the most recent lab report.
Review HOMA-IR — a value above 2.5-3.0 indicates insulin resistance.
Check QUICKI and HOMA-%B (beta-cell function) for a fuller picture of insulin dynamics.
Use Resistance Level (0-3) to stratify patients for lifestyle intervention or pharmacotherapy.

How the result changes with Fasting Insulin (µU/mL)

Fasting Insulin (µU/mL)	HOMA-IR
30	6.67
105	23.33
195	43.33
270	60

What each input means

Fasting Insulin (µU/mL): Fasting serum insulin level in micro-units per milliliter.
Fasting Glucose (mg/dL): Fasting blood glucose in mg/dL. Multiply mmol/L × 18 to convert.
HbA1c (%): Glycated hemoglobin percentage for estimated average glucose.

What each result means

HOMA-IR: Homeostatic Model Assessment of Insulin Resistance. <1 optimal, 1–1.9 normal, 2–2.9 early resistance, ≥3 significant resistance.
HOMA-%B (β-cell function): Estimated pancreatic β-cell function (%). Higher values indicate greater insulin secretion capacity.
QUICKI: Quantitative Insulin Sensitivity Check Index. Normal ≈ 0.35–0.40; lower values suggest resistance.
Est. Average Glucose (mg/dL): Estimated average glucose derived from HbA1c using ADAG formula: eAG = 28.7 × A1c − 46.7.
Resistance Level (0–3): 0 = Optimal, 1 = Normal, 2 = Early insulin resistance, 3 = Significant insulin resistance.

How this is calculated

Worked example, using the default values

Identify Input Parameters
Fasting Insulin (µU/mL) = 8, Fasting Glucose (mg/dL) = 90, HbA1c (%) = 5.6 = 3 input(s) provided
Calculate HOMA-IR
HOMA-IR = (fastingInsulin * fastingGlucose) / 405
1.78 = 1.78
Calculate HOMA-%B
106.7 = 106.7
Calculate QUICKI
QUICKI = 1 / (log10(max(0.1, fastingInsulin)) + log10(max(1, fastingGlucose)))
0.35 = 0.35