Pancreatic Enzyme Dosing Calculator
Calculate pancreatic enzyme replacement therapy (PERT) lipase dosing by weight and fat intake. Includes capsule counts, safety limits, and monthly supply estimates.
Medical Disclaimer
This calculator is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about your health. Never disregard professional medical advice or delay seeking it because of results from this tool.
Inputs
Results
Lipase per Meal (units)
70,000
Daily Lipase Total (units)
280,000
How to Use This Calculator
- Enter the patient's Body Weight in kg and number of Meals Per Day and Snacks Per Day.
- Enter Fat Grams Per Meal to refine dosing for fat malabsorption.
- Enter the Capsule Strength in lipase units available and the Dosing Level (0–3 scale).
- Review Lipase Per Meal and Lipase Per Snack to determine how many capsules to take at each eating occasion.
- Check Daily Lipase Total and Capsules Per Meal to confirm the dose is within safe limits.
How the result changes with Body Weight (kg)
| Body Weight (kg) | Lipase per Meal (units) | Daily Lipase Total (units) |
|---|---|---|
| 28 | 40,000 | 160,000 |
| 89 | 89,000 | 356,000 |
| 164 | 164,000 | 656,000 |
| 225 | 225,000 | 900,000 |
What each input means
- Body Weight (kg)
- Patient body weight in kilograms.
- Meals per Day
- Number of full meals per day.
- Snacks per Day
- Number of snacks per day. Snack dose is ~50% of meal dose.
- Fat per Meal (grams)
- Average grams of fat per meal for fat-based dosing calculation.
- Capsule Strength (lipase units)
- Lipase units per capsule. Common: 3000, 6000, 12000, 24000, 36000.
- Dosing Level (0–3)
- 0 = starting (500 U/kg/meal), 1 = moderate (1000), 2 = high (1500), 3 = maximum (2500).
What each result means
- Lipase per Meal (units)
- Recommended lipase units per full meal.
- Lipase per Snack (units)
- Recommended lipase units per snack (~50% of meal dose).
- Daily Lipase Total (units)
- Total daily lipase from meals and snacks (capped at safety maximum).
- Capsules per Meal
- Number of capsules needed per meal based on selected strength.
- Capsules per Snack
- Number of capsules needed per snack.
- Daily Capsule Count
- Total capsules needed per day.
- Monthly Capsule Supply
- Estimated 30-day capsule supply needed.
- Exceeds Max Dose (0/1)
- 1 = calculated dose exceeds safety limit of 10,000 lipase units/kg/day.
- Max Daily Allowed (units)
- Maximum safe daily lipase dose (10,000 units/kg/day).
- Fat-Based Dose per Meal
- Alternative dose calculated from dietary fat content (2000 U/g fat).
How this is calculated
Worked example, using the default values
- Identify Input Parameters4 parametersBody Weight (kg) = 70, Meals per Day = 3, Snacks per Day = 2, Fat per Meal (grams) = 20 = 6 input(s) provided
- Calculate Lipase per MealLipase per Meal = max(lipasePerMeal, fatBasedDose)70000 = 70000
- Calculate Daily Lipase TotalDaily Lipase Total = min(dailyTotal, maxDailyDose)280000 = 280000
- Calculate Lipase per SnackLipase per Snack = round(recommendedPerMeal * 0.5)35000 = 35000
- Calculate Capsules per MealCapsules per Meal3 = 3
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